Cyclophosphamide 1 gm Injection

Cyclophosphamide for Injection IP

Indications :

Malignant Disease :

• Malignant lymphomas (Stages III and IV of the Ann Arbor staging system).

• Non-Malignant Disease : Biopsy proven minimal change nephrotic syndrome in children

• Hodgkin's disease, lymphocytic lymphoma (nodular or diffuse), Mixed-cell type lymphoma.

• Histiocytic lymphoma.

• Burkitt's lymphoma.

• Multiple myeloma.

• Mycosis Fungoides

Dosage :

ADULTS AND CHILDREN :
Single oncolytic drug therapy : 40 to 50 mg/kg IV in divided doses over a period of 2 to 5 days.
Other intravenous regimens included : 10 to 15 mg/kg given every 7 to 10 days or 3 to 5 mg/kg twice weekly.
General Intravenous Dosage : 40-50 mg/kg intravenously in divided doses over a period of 2-5 days.

Dosage Adjustment :
Renal Impairment : Required.
Hepatic Impairment : Not required.