Methotrexate 2.5 mg Tablet

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Product Code : ON-I46

Product Description

Methotrexate 2.5 mg Tablet

Indications :

Trophoblastic neoplasms (chorioadenoma destruens, choriocarcinoma, and hydatidiform mole).
Acute lymphocytic leukemia (ALL)
Meningeal leukemia or meningeal leukemia
Breast cancer
Head and neck cancer
Cutaneous T-cell lymphoma (mycosis fungoides)
Lung cancer
Non-Hodgkin's lymphoma (NHL)
Burkitt's Lymphoma
Osteogenic sarcoma

Dosage :

Trophoblastic Neoplasms Adults : 15-30mg peroral (PO)/ intramuscular (IM) once daily, given for 5 days.

Acute Lymphocyic Leukemia Adults & children : 3.3mg/m² IV daily for 4-6 weeks or followed by maintenance therapy with 20-30mg/m²/PO/IM given twice weekly.

Breast Cancer Adults & Children : 40-60mg/m² IV given on day 1 of every 21-28 days along with cyclophosphamide & fluorouracil.

Head & Neck Cancer Adults & Children : 40mg/m² IV on days 1 & 15 of every 21 days alone or with bleomycin & cisplatin.

Cutaneous T-cell Lymphoma Adults : 50mg IM once weekly or 25mg twice weekly.

Lung Cancer : Methotrexate 20mg/m² IV as a single dose along with cisplatin, doxorubicin & cyclophosphamide repeated every 28 days.

Dosage Adjustment :

Renal Impairment : Required.

Hepatic Impairment : Required.